By Derrick Stanley
According to data published online ahead of print in the journal Epilepsy & Behavior, the administration of whole-plant cannabis extracts rich in the cannabinoid cannabidol (CBD) is associated with reduced seizure frequency in patients with refractory epilepsy,
Researchers reviewed the charts of 272 patients who were taking whole-plant CBD extracts.
Eighty-six percent of those treated observed a reduction in seizure frequency, while ten percent experienced a complete clinical response.
Beneficial side effects were reported, such as better sleep quality, improved mood, and increased appetite.
“The cannabinoids’ novel mechanisms of action are an attractive consideration for possible seizure control,” authors concluded. “In patients with refractory epilepsy that have a low likelihood of responding to a subsequent AED (anti-epileptic drug), a trial of artisanal cannabis formulas may be indicated.”